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Adenosine accelerates the healing of diabetic ischemic ulcers by improving autophagy of endothelial progenitor cells grown on a biomaterial

Endothelial progenitor cells (EPCs) seeded on biomaterials can effectively promote diabetic ischemic wound healing. However, the function of transplanted EPCs is negatively affected by a high-glucose and ischemic microenvironment. Our experiments showed that EPC autophagy was inhibited and mitochond...

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Detalles Bibliográficos
Autores principales: Chen, Wen, Wu, Yangxiao, Li, Li, Yang, Mingcan, Shen, Lei, Liu, Ge, Tan, Ju, Zeng, Wen, Zhu, Chuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479873/
https://www.ncbi.nlm.nih.gov/pubmed/26108983
http://dx.doi.org/10.1038/srep11594