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Secreted trophic factors of Human umbilical cord stromal cells induce differentiation and neurite extension through PI3K and independent of cAMP pathway

BACKGROUND: Trophic factors (TFs) play important role during development and adult tissue maintenance. In neurodegenerative diseases (ND) TF supplementation provides protection. Stromal cells (HUMS) derived from the human umbilical cord matrix provide neuroprotection in the ND models of mice. PURPOS...

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Detalles Bibliográficos
Autores principales: Kumar, Ajeet, Mishra, Himanshu K, Dwivedi, Priyanka, Subramaniam, Jamuna R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Academy of Neurosciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480253/
https://www.ncbi.nlm.nih.gov/pubmed/26130914
http://dx.doi.org/10.5214/ans.0972.7531.220208