Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells

Type 1 diabetes (T1D) is an autoimmune disease caused by loss of pancreatic β cells via apoptosis while neighboring α cells are preserved. Viral infections by coxsackieviruses (CVB) may contribute to trigger autoimmunity in T1D. Cellular permissiveness to viral infection is modulated by innate antiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Marroqui, Laura, Lopes, Miguel, dos Santos, Reinaldo S, Grieco, Fabio A, Roivainen, Merja, Richardson, Sarah J, Morgan, Noel G, Op de beeck, Anne, Eizirik, Decio L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480275/
https://www.ncbi.nlm.nih.gov/pubmed/26061776
http://dx.doi.org/10.7554/eLife.06990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480275/
https://www.ncbi.nlm.nih.gov/pubmed/26061776
http://dx.doi.org/10.7554/eLife.06990

Ejemplares similares