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Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells

Type 1 diabetes (T1D) is an autoimmune disease caused by loss of pancreatic β cells via apoptosis while neighboring α cells are preserved. Viral infections by coxsackieviruses (CVB) may contribute to trigger autoimmunity in T1D. Cellular permissiveness to viral infection is modulated by innate antiv...

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Detalles Bibliográficos
Autores principales:	Marroqui, Laura, Lopes, Miguel, dos Santos, Reinaldo S, Grieco, Fabio A, Roivainen, Merja, Richardson, Sarah J, Morgan, Noel G, Op de beeck, Anne, Eizirik, Decio L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480275/ https://www.ncbi.nlm.nih.gov/pubmed/26061776 http://dx.doi.org/10.7554/eLife.06990

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