Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation

BACKGROUND: Survivors of critical illness are at increased risk of fractures. This may be due to increased osteoclast formation during critical illness, leading to trabecular bone loss. Such bone loss has also been observed in Paget’s disease, and has been related to deficient autophagy. Deficient a...

Descripción completa

Detalles Bibliográficos
Autores principales: Owen, Helen C, Vanhees, Ineke, Gunst, Jan, Van Cromphaut, Sophie, Van den Berghe, Greet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480347/
https://www.ncbi.nlm.nih.gov/pubmed/26215816
http://dx.doi.org/10.1186/s40635-015-0052-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480347/
https://www.ncbi.nlm.nih.gov/pubmed/26215816
http://dx.doi.org/10.1186/s40635-015-0052-3

Ejemplares similares