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Critical illness-induced bone loss is related to deficient autophagy and histone hypomethylation
BACKGROUND: Survivors of critical illness are at increased risk of fractures. This may be due to increased osteoclast formation during critical illness, leading to trabecular bone loss. Such bone loss has also been observed in Paget’s disease, and has been related to deficient autophagy. Deficient a...
Autores principales: | Owen, Helen C, Vanhees, Ineke, Gunst, Jan, Van Cromphaut, Sophie, Van den Berghe, Greet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480347/ https://www.ncbi.nlm.nih.gov/pubmed/26215816 http://dx.doi.org/10.1186/s40635-015-0052-3 |
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