Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice

Pak1 plays an important role in various cellular processes, including cell motility, polarity, survival and proliferation. To date, its role in atherogenesis has not been explored. Here we report the effect of Pak1 on atherogenesis using atherosclerosis-prone apolipoprotein E-deficient (ApoE(−/−)) m...

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Detalles Bibliográficos
Autores principales: Singh, Nikhlesh K., Kotla, Sivareddy, Dyukova, Elena, Traylor Jr., James G., Orr, A. Wayne, Chernoff, Jonathan, Marion, Tony N., Rao, Gadiparthi N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480433/
https://www.ncbi.nlm.nih.gov/pubmed/26104863
http://dx.doi.org/10.1038/ncomms8450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480433/
https://www.ncbi.nlm.nih.gov/pubmed/26104863
http://dx.doi.org/10.1038/ncomms8450

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