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Pharmacokinetic analysis of the chronic administration of the inert gases Xe and Ar using a physiological based model

BACKGROUND: New gas therapies using inert gases such as xenon and argon are being studied, which would require chronically administered repeating doses. The pharmacokinetics of this type of administration has not been addressed in the literature. METHODS: A physiologically based pharmacokinetics (PB...

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Detalles Bibliográficos
Autores principales: Katz, Ira, Murdock, Jacqueline, Palgen, Marc, Pype, Jan, Caillibotte, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480577/
https://www.ncbi.nlm.nih.gov/pubmed/26113973
http://dx.doi.org/10.1186/s13618-015-0029-z