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Effect of Matrine on HPAC cell migration by down-regulating the expression of MT1-MMP via Wnt signaling

AIM: This study sought to explore the exact mechanism of Matrine inhibited migration and invasion of human pancreatic cancer cells. METHODS: HPAC or Capan-1 cells were cultured in completed RPMI-1640 medium, contained with 50 μg/ml Matrine or 0.05 μg/ml docetaxel, respectively. Cell viability was ev...

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Detalles Bibliográficos
Autores principales: Ma, Yongchao, Zou, Fazhang, Xiong, Junping, Wan, Wei, Yin, Li, Li, Xianjia, Bei, Zhanyu, Yuan, Lei, Meng, Song, Wang, Jianguo, Song, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480578/
https://www.ncbi.nlm.nih.gov/pubmed/26113801
http://dx.doi.org/10.1186/s12935-015-0210-4