Deficiency of AMPK in CD8(+) T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death

A number of studies have linked AMPK, a major metabolic sensor coordinating of multiple cellular functions, to tumor development and progression. However, the exact role of AMPK in tumor development is still controversial. Here we report that activation of AMPK promotes survival and anti-tumor funct...

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Detalles Bibliográficos
Autores principales: Rao, Enyu, Zhang, Yuwen, Zhu, Ganqian, Hao, Jiaqing, Persson, Xuan-Mai T., Egilmez, Nejat K., Suttles, Jill, Li, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480727/
https://www.ncbi.nlm.nih.gov/pubmed/25760243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480727/
https://www.ncbi.nlm.nih.gov/pubmed/25760243

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