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Activation of NRF2 by p62 and proteasome reduction in sphere-forming breast carcinoma cells

Cancer stem cells (CSCs) express high levels of drug efflux transporters and antioxidant genes, and are therefore believed to be responsible for cancer recurrence following chemo/radiotherapy intervention. In this study, we investigated the role of NF-E2-related factor 2 (NRF2), a master regulator o...

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Detalles Bibliográficos
Autores principales: Ryoo, In-geun, Choi, Bo-hyun, Kwak, Mi-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480743/
https://www.ncbi.nlm.nih.gov/pubmed/25717032