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Blood-brain barrier permeability of gefitinib in patients with brain metastases from non-small-cell lung cancer before and during whole brain radiation therapy

INTRODUCTION: To explore the ability of gefitinib to penetrate blood brain barrier (BBB) during whole brain radiation therapy (WBRT). PATIENTS AND METHODS: Enrolled in this study were eligible patients who were diagnosed with BM from NSCLC. Gefitinib was given at 250 mg/day for 30 days, then concurr...

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Detalles Bibliográficos
Autores principales: Zeng, Yin-duo, Liao, Hai, Qin, Tao, Zhang, Li, Wei, Wei-dong, Liang, Jian-zhong, Xu, Fei, Dinglin, Xiao-xiao, Ma, Shu-xiang, Chen, Li-kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480758/
https://www.ncbi.nlm.nih.gov/pubmed/25788260