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Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs)

BACKGROUND: Over the past 50,000 years, shifts in human-environmental or human-human interactions shaped genetic differences within and among human populations, including variants under positive selection. Shaped by environmental factors, such variants influence the genetics of modern health, diseas...

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Detalles Bibliográficos
Autores principales: Handelman, Samuel K, Seweryn, Michal, Smith, Ryan M, Hartmann, Katherine, Wang, Danxin, Pietrzak, Maciej, Johnson, Andrew D, Kloczkowski, Andrzej, Sadee, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480832/
https://www.ncbi.nlm.nih.gov/pubmed/26111110
http://dx.doi.org/10.1186/1471-2164-16-S8-S8