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Conditional entropy in variation-adjusted windows detects selection signatures associated with expression quantitative trait loci (eQTLs)
BACKGROUND: Over the past 50,000 years, shifts in human-environmental or human-human interactions shaped genetic differences within and among human populations, including variants under positive selection. Shaped by environmental factors, such variants influence the genetics of modern health, diseas...
Autores principales: | Handelman, Samuel K, Seweryn, Michal, Smith, Ryan M, Hartmann, Katherine, Wang, Danxin, Pietrzak, Maciej, Johnson, Andrew D, Kloczkowski, Andrzej, Sadee, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480832/ https://www.ncbi.nlm.nih.gov/pubmed/26111110 http://dx.doi.org/10.1186/1471-2164-16-S8-S8 |
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