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A Novel Synthesized Sulfonamido-Based Gallate—JEZ-C as Potential Therapeutic Agents for Osteoarthritis

Gallic acid (GA) and its derivatives are anti-inflammatory agents reported to have an effect on osteoarthritis (OA). However, GA has much weaker anti-oxidant effects and inferior bioactivity compared with its derivatives. We modified GA with the introduction of sulfonamide to synthesize a novel comp...

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Detalles Bibliográficos
Autores principales: Wei, Shixiu, Lu, Zhenhui, Zou, Yunfeng, Lin, Xiao, Lin, Cuiwu, Liu, Buming, Zheng, Li, Zhao, Jinmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480854/
https://www.ncbi.nlm.nih.gov/pubmed/26107568
http://dx.doi.org/10.1371/journal.pone.0125930