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Nur77 deficiency leads to systemic inflammation in elderly mice

BACKGROUND: Nur77, an orphan member of the nuclear receptor superfamily, has been implicated in the regulation of inflammation. However, the in vivo function of Nur77 remains largely unexplored. In the current study, we investigated the role of Nur77 in inflammation and immunity in mice. FINDINGS: W...

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Detalles Bibliográficos
Autores principales: Li, Xiu-Ming, Lu, Xing-Xing, Xu, Qian, Wang, Jing-Ru, Zhang, Shen, Guo, Peng-Da, Li, Jian-Ming, Wu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480882/
https://www.ncbi.nlm.nih.gov/pubmed/26113803
http://dx.doi.org/10.1186/s12950-015-0085-0