Dexamethasone enhances programmed cell death 1 (PD-1) expression during T cell activation: an insight into the optimum application of glucocorticoids in anti-cancer therapy

BACKGROUND: Programmed cell death 1 (PD-1) is a key cell-surface receptor of CD28 superfamily that triggers inhibitory pathways to attenuate T-cell responses and promote T-cell tolerance. As a crucial role in tumor immunity, PD-1 has been a focus of studies in anti-cancer therapy. It has been approv...

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Detalles Bibliográficos
Autores principales: Xing, Kailin, Gu, Bingxin, Zhang, Ping, Wu, Xianghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480888/
https://www.ncbi.nlm.nih.gov/pubmed/26112261
http://dx.doi.org/10.1186/s12865-015-0103-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480888/
https://www.ncbi.nlm.nih.gov/pubmed/26112261
http://dx.doi.org/10.1186/s12865-015-0103-2

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