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High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins
INTRODUCTION: Takayasu arteritis (TA) and giant cell arteritis (GCA) are large vessel vasculitides (LVV) that usually present as granulomatous inflammation in arterial walls. High mobility group box 1 (HMGB1) is a nuclear protein that acts as an alarmin when released by dying or activated cells. Thi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480896/ https://www.ncbi.nlm.nih.gov/pubmed/26062541 http://dx.doi.org/10.1186/s13075-015-0672-8 |