High mobility group box 1 levels in large vessel vasculitis are not associated with disease activity but are influenced by age and statins

INTRODUCTION: Takayasu arteritis (TA) and giant cell arteritis (GCA) are large vessel vasculitides (LVV) that usually present as granulomatous inflammation in arterial walls. High mobility group box 1 (HMGB1) is a nuclear protein that acts as an alarmin when released by dying or activated cells. Thi...

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Detalles Bibliográficos
Autores principales: de Souza, Alexandre W. S., van der Geest, Kornelis S. M., Brouwer, Elisabeth, Pinheiro, Frederico A. G., Oliveira, Ana Cecília Diniz, Sato, Emília Inoue, Andrade, Luis Eduardo C., Bijl, Marc, Westra, Johanna, Kallenberg, Cees G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480896/
https://www.ncbi.nlm.nih.gov/pubmed/26062541
http://dx.doi.org/10.1186/s13075-015-0672-8

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