The Human IL-22 Receptor Is Regulated through the Action of the Novel E3 Ligase Subunit FBXW12, Which Functions as an Epithelial Growth Suppressor

Interleukin- (IL-) 22 signaling is protective in animal models of pneumonia and bacteremia by Klebsiella pneumoniae and mediates tissue recovery from influenza and Staph aureus infection. We recently described processing of mouse lung epithelial IL-22 receptor (IL-22R) by ubiquitination on the intra...

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Detalles Bibliográficos
Autores principales: Franz, Joseph, Jerome, Jacob, Lear, Travis, Gong, Qiaoke, Weathington, Nathaniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480942/
https://www.ncbi.nlm.nih.gov/pubmed/26171402
http://dx.doi.org/10.1155/2015/912713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480942/
https://www.ncbi.nlm.nih.gov/pubmed/26171402
http://dx.doi.org/10.1155/2015/912713

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