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Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice

RATIONALE: While brain serotonin (5-HT) function is implicated in gene-by-environment interaction (GxE) impacting the vulnerability-resilience continuum in neuropsychiatric disorders, it remains elusive how the interplay of altered 5-HT synthesis and environmental stressors is linked to failure in e...

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Detalles Bibliográficos
Autores principales: Gutknecht, Lise, Popp, Sandy, Waider, Jonas, Sommerlandt, Frank M. J., Göppner, Corinna, Post, Antonia, Reif, Andreas, van den Hove, Daniel, Strekalova, Tatyana, Schmitt, Angelika, Colaςo, Maria B. N., Sommer, Claudia, Palme, Rupert, Lesch, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480945/
https://www.ncbi.nlm.nih.gov/pubmed/25716307
http://dx.doi.org/10.1007/s00213-015-3879-0