Cargando…

Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice

RATIONALE: While brain serotonin (5-HT) function is implicated in gene-by-environment interaction (GxE) impacting the vulnerability-resilience continuum in neuropsychiatric disorders, it remains elusive how the interplay of altered 5-HT synthesis and environmental stressors is linked to failure in e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gutknecht, Lise, Popp, Sandy, Waider, Jonas, Sommerlandt, Frank M. J., Göppner, Corinna, Post, Antonia, Reif, Andreas, van den Hove, Daniel, Strekalova, Tatyana, Schmitt, Angelika, Colaςo, Maria B. N., Sommer, Claudia, Palme, Rupert, Lesch, Klaus-Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2015
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480945/ https://www.ncbi.nlm.nih.gov/pubmed/25716307 http://dx.doi.org/10.1007/s00213-015-3879-0

Ejemplares similares

Impacts of Brain Serotonin Deficiency following Tph2 Inactivation on Development and Raphe Neuron Serotonergic Specification
por: Gutknecht, Lise, et al.
Publicado: (2012)

Identification of Cholecystokinin by Genome-Wide Profiling as Potential Mediator of Serotonin-Dependent Behavioral Effects of Maternal Separation in the Amygdala
por: Weidner, Magdalena T., et al.
Publicado: (2019)

Conservation of 5-HT(1A) receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis
por: Araragi, Naozumi, et al.
Publicado: (2013)

Association between Serotonin-Related Polymorphisms in 5HT2A, TPH1, TPH2 Genes and Bipolar Disorder in Korean Population
por: Choi, Kwang-Yeon, et al.
Publicado: (2010)

Experimental heart failure causes depression-like behavior together with differential regulation of inflammatory and structural genes in the brain
por: Frey, Anna, et al.
Publicado: (2014)

REVERSE phenotyping—Can the phenotype following constitutive Tph2 gene inactivation in mice be transferred to children and adolescents with and without adhd?
por: Akhrif, Atae, et al.
Publicado: (2021)

Transcriptome of pancreas-specific Bmpr1a-deleted islets links to TPH1–5-HT axis
por: Jiang, Fang-Xu, et al.
Publicado: (2015)

[6]-Gingerol Ameliorates Cisplatin-Induced Pica by Regulating the TPH/MAO-A/SERT/5-HT/5-HT(3) Receptor System in Rats
por: Cheng, Qianqian, et al.
Publicado: (2020)

Serotonin Exhibits Accelerated Bleomycin-Induced Pulmonary Fibrosis through TPH1 Knockout Mouse Experiments
por: Zhang, Jingyao, et al.
Publicado: (2018)

Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders
por: Wigner, Paulina, et al.
Publicado: (2018)

Generation of a Tph2 Conditional Knockout Mouse Line for Time- and Tissue-Specific Depletion of Brain Serotonin
por: Pelosi, Barbara, et al.
Publicado: (2015)

Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis
por: González-Castro, Thelma Beatriz, et al.
Publicado: (2014)

Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach
por: Anttila, Sami, et al.
Publicado: (2007)

Serotonin transporter genotype modulates resting state and predator stress-induced amygdala perfusion in mice in a sex-dependent manner
por: Kolter, Jann F., et al.
Publicado: (2021)

Tph Cells Expanded in Primary Sjögren’s Syndrome
por: Chen, Weiqian, et al.
Publicado: (2022)

Polymorphism of the Tryptophan Hydroxylase 2 (TPH2) Gene Is Associated with Chimpanzee Neuroticism
por: Hong, Kyung-Won, et al.
Publicado: (2011)

Associations Between Variations in TPH1 , TPH2 and SLC6A4 Genes and Postpartum Depression: A Study in the Jordanian Population
por: Khabour, OF, et al.
Publicado: ( 201)

The Interaction of TPH2 and 5-HT2A Polymorphisms on Major Depressive Disorder Susceptibility in a Chinese Han Population: A Case-Control Study
por: Yang, Jiarun, et al.
Publicado: (2019)

TPH1 and 5-HT(7) Receptor Overexpression Leading to Gemcitabine-Resistance Requires Non-Canonical Permissive Action of EZH2 in Pancreatic Ductal Adenocarcinoma
por: Chaudhary, Prakash, et al.
Publicado: (2021)

Serotonin Deficiency Increases Context-Dependent Fear Learning Through Modulation of Hippocampal Activity
por: Waider, Jonas, et al.
Publicado: (2019)

Mutational Analysis Gives Insight into Substrate Preferences of a Nucleotidyl Cyclase from Mycobacterium avium
por: Syed, Wajeed, et al.
Publicado: (2014)

Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain
por: Forero, Andrea, et al.
Publicado: (2017)

Effects of the Combination of the C1473G Mutation in the Tph2 Gene and Lethal Yellow Mutations in the Raly-Agouti Locus on Behavior, Brain 5-HT and Melanocortin Systems in Mice
por: Komleva, Polyna D., et al.
Publicado: (2023)

TPH2 Gene Polymorphisms and Major Depression – A Meta-Analysis
por: Gao, Jin, et al.
Publicado: (2012)

Alternative Splicing and Extensive RNA Editing of Human TPH2 Transcripts
por: Grohmann, Maik, et al.
Publicado: (2010)

TPH1 A218C polymorphism and temperament in major depression
por: Andre, Kadri, et al.
Publicado: (2013)

Structural basis of terephthalate recognition by solute binding protein TphC
por: Gautom, Trishnamoni, et al.
Publicado: (2021)

Tph2 Gene Expression Defines Ethanol Drinking Behavior in Mice
por: Zaniewska, Magdalena, et al.
Publicado: (2022)

The Promotion and Development of One Health at Swiss TPH and Its Greater Potential
por: Zinsstag, Jakob, et al.
Publicado: (2022)

Serotonergic modulation of normal and abnormal brain dynamics: The genetic influence of the TPH2 G-703T genotype and DNA methylation on wavelet variance in children and adolescents with and without ADHD
por: Akhrif, Atae, et al.
Publicado: (2023)

Association Study between Promoter Polymorphism of TPH1 and Progression of Idiopathic Scoliosis
por: Yablanski, Vasil, et al.
Publicado: (2016)

An Ancient Mutation in the TPH1 Gene is Consistent with the Changes in Mammalian Reproductive Rhythm
por: Liu, Chenhui, et al.
Publicado: (2019)

Polymorphism of TPH2 Gene rs120074175 Is Not Associated with Risk Factors of Schizophrenia
por: Laksono, James P., et al.
Publicado: (2019)

Impaired Social Behavior in 5-HT(3A) Receptor Knockout Mice
por: Smit-Rigter, Laura A., et al.
Publicado: (2010)

Serotonin deficiency induced after brain maturation rescues consequences of early life adversity
por: Aboagye, B., et al.
Publicado: (2021)

TPH2 polymorphisms and expression in Prader-Willi syndrome subjects with differing genetic subtypes
por: Henkhaus, Rebecca S., et al.
Publicado: (2010)

Characterization of mammary-specific disruptions for Tph1 and Lrp5 during murine lactation
por: Weaver, Samantha R., et al.
Publicado: (2017)

TPH-2 Gene Polymorphism in Major Depressive Disorder Patients With Early-Wakening Symptom
por: Tao, Shiwan, et al.
Publicado: (2018)

The Interaction of TPH1 A779C Polymorphism and Maternal Authoritarianism on Creative Potential
por: Zhang, Jinghuan, et al.
Publicado: (2018)

Plant-Soil-Microbiota Combination for the Removal of Total Petroleum Hydrocarbons (TPH): An In-Field Experiment
por: Zuzolo, Daniela, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qiu0jflj9kpmod6nemua926auh