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In Vivo Induction of Functionally Suppressive Induced Regulatory T Cells from CD4(+)CD25(-) T Cells Using an Hsp70 Peptide
Therapeutic peptides that target antigen-specific regulatory T cells (Tregs) can suppress experimental autoimmune diseases. The heat shock protein (Hsp) 70, with its expression elevated in inflamed tissue, is a suitable candidate antigen because administration of both bacterial and mouse Hsp70 pepti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481099/ https://www.ncbi.nlm.nih.gov/pubmed/26107957 http://dx.doi.org/10.1371/journal.pone.0128373 |