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Identification of miR-26a as a Target Gene of Bile Acid Receptor GPBAR-1/TGR5

GPBAR1/TGR5 is a G protein–coupled receptor of bile acids. TGR5 is known to regulate the BA homeostasis and energy metabolism. Recent studies highlight an important role of TGR5 in alleviating obesity and improving glucose regulation, however, the mechanism of which is still unclear. Here we report...

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Detalles Bibliográficos
Autores principales: Chen, Xiaosong, Xu, Haixia, Ding, Lili, Lou, Guiyu, Liu, Yan, Yao, Yalan, Chen, Liangwan, Huang, Wendong, Fu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481113/
https://www.ncbi.nlm.nih.gov/pubmed/26107166
http://dx.doi.org/10.1371/journal.pone.0131294