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Inhibitory Receptors Beyond T Cell Exhaustion
Inhibitory receptors (iRs) are frequently associated with “T cell exhaustion”. However, the expression of iRs is also dependent on T cell differentiation and activation. Therapeutic blockade of various iRs, also referred to as “checkpoint blockade”, is showing unprecedented results in the treatment...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481276/ https://www.ncbi.nlm.nih.gov/pubmed/26167163 http://dx.doi.org/10.3389/fimmu.2015.00310 |