Orchestrating an immune response against cancer with engineered immune cells expressing αβTCRs, CARs, and innate immune receptors: an immunological and regulatory challenge

Over half a century ago, the first allogeneic stem cell transplantation (allo-SCT) initiated cellular immunotherapy. For several decades, little progress was made, and toxicity of allo-SCT remained a major challenge. However, recent breakthroughs have opened new avenues to further develop this modal...

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Detalles Bibliográficos
Autores principales: de Witte, Moniek A., Kierkels, Guido J. J., Straetemans, Trudy, Britten, Cedrik M., Kuball, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Focussed Research Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481298/
https://www.ncbi.nlm.nih.gov/pubmed/25990073
http://dx.doi.org/10.1007/s00262-015-1710-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481298/
https://www.ncbi.nlm.nih.gov/pubmed/25990073
http://dx.doi.org/10.1007/s00262-015-1710-8

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