Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping

Identification of candidate causal variants in regions associated with risk of common diseases is complicated by linkage disequilibrium (LD) and multiple association signals. Nonetheless, accurate maps of these variants are needed, both to fully exploit detailed cell specific chromatin annotation da...

Descripción completa

Detalles Bibliográficos
Autores principales: Wallace, Chris, Cutler, Antony J, Pontikos, Nikolas, Pekalski, Marcin L, Burren, Oliver S, Cooper, Jason D, García, Arcadio Rubio, Ferreira, Ricardo C, Guo, Hui, Walker, Neil M, Smyth, Deborah J, Rich, Stephen S, Onengut-Gumuscu, Suna, Sawcer, Stephen J, Ban, Maria, Richardson, Sylvia, Todd, John A, Wicker, Linda S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481316/
https://www.ncbi.nlm.nih.gov/pubmed/26106896
http://dx.doi.org/10.1371/journal.pgen.1005272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481316/
https://www.ncbi.nlm.nih.gov/pubmed/26106896
http://dx.doi.org/10.1371/journal.pgen.1005272

Ejemplares similares