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Tetraarsenictetrasulfide and Arsenic Trioxide Exert Synergistic Effects on Induction of Apoptosis and Differentiation in Acute Promyelocytic Leukemia Cells

Since arsenic trioxide (As(3+)) has been successfully used in the treatment of acute promyelocytic leukemia (APL), its adverse effects on patients have been problematic and required a solution. Considering the good therapeutic potency and low toxicity of tetraarsenictetrasulfide (As(4)S(4)) in the t...

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Detalles Bibliográficos
Autores principales: Wang, Shuping, Zhou, Min, Ouyang, Jian, Geng, Zhirong, Wang, Zhilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481354/
https://www.ncbi.nlm.nih.gov/pubmed/26110921
http://dx.doi.org/10.1371/journal.pone.0130343