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Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections

Novel antimicrobials and new approaches to developing them are urgently needed. Repurposing already-approved drugs with well-characterized toxicology and pharmacology is a novel way to reduce the time, cost, and risk associated with antibiotic innovation. Ebselen, an organoselenium compound, is know...

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Detalles Bibliográficos
Autores principales: Thangamani, Shankar, Younis, Waleed, Seleem, Mohamed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481386/
https://www.ncbi.nlm.nih.gov/pubmed/26111644
http://dx.doi.org/10.1038/srep11596