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Comparative study of the effectiveness and limitations of current methods for detecting sequence coevolution

Motivation: With rapid accumulation of sequence data on several species, extracting rational and systematic information from multiple sequence alignments (MSAs) is becoming increasingly important. Currently, there is a plethora of computational methods for investigating coupled evolutionary changes...

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Detalles Bibliográficos
Autores principales: Mao, Wenzhi, Kaya, Cihan, Dutta, Anindita, Horovitz, Amnon, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481699/
https://www.ncbi.nlm.nih.gov/pubmed/25697822
http://dx.doi.org/10.1093/bioinformatics/btv103