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Inferring models of multiscale copy number evolution for single-tumor phylogenetics

Motivation: Phylogenetic algorithms have begun to see widespread use in cancer research to reconstruct processes of evolution in tumor progression. Developing reliable phylogenies for tumor data requires quantitative models of cancer evolution that include the unusual genetic mechanisms by which tum...

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Detalles Bibliográficos
Autores principales: Chowdhury, Salim Akhter, Gertz, E. Michael, Wangsa, Darawalee, Heselmeyer-Haddad, Kerstin, Ried, Thomas, Schäffer, Alejandro A., Schwartz, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481700/
https://www.ncbi.nlm.nih.gov/pubmed/26072490
http://dx.doi.org/10.1093/bioinformatics/btv233