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IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection

Initial events after exposure determine HIV-1 disease progression, underscoring a critical need to understand host mechanisms that interfere with initial viral replication. Although associated with chronic HIV-1 control, it is not known whether interleukin-21 (IL-21) contributes to early HIV-1 immun...

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Detalles Bibliográficos
Autores principales: Adoro, Stanley, Cubillos-Ruiz, Juan R., Chen, Xi, Deruaz, Maud, Vrbanac, Vladimir D., Song, Minkyung, Park, Suna, Murooka, Thomas T., Dudek, Timothy E., Luster, Andrew D., Tager, Andrew M., Streeck, Hendrik, Bowman, Brittany, Walker, Bruce D., Kwon, Douglas S., Lazarevic, Vanja, Glimcher, Laurie H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481879/
https://www.ncbi.nlm.nih.gov/pubmed/26108174
http://dx.doi.org/10.1038/ncomms8562