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Orientation of DNA Minicircles Balances Density and Topological Complexity in Kinetoplast DNA

Kinetoplast DNA (kDNA), a unique mitochondrial structure common to trypanosomatid parasites, contains thousands of DNA minicircles that are densely packed and can be topologically linked into a chain mail-like network. Experimental data indicate that every minicircle in the network is, on average, s...

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Detalles Bibliográficos
Autores principales: Diao, Yuanan, Rodriguez, Victor, Klingbeil, Michele, Arsuaga, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482025/
https://www.ncbi.nlm.nih.gov/pubmed/26110537
http://dx.doi.org/10.1371/journal.pone.0130998