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Orientation of DNA Minicircles Balances Density and Topological Complexity in Kinetoplast DNA
Kinetoplast DNA (kDNA), a unique mitochondrial structure common to trypanosomatid parasites, contains thousands of DNA minicircles that are densely packed and can be topologically linked into a chain mail-like network. Experimental data indicate that every minicircle in the network is, on average, s...
Autores principales: | Diao, Yuanan, Rodriguez, Victor, Klingbeil, Michele, Arsuaga, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482025/ https://www.ncbi.nlm.nih.gov/pubmed/26110537 http://dx.doi.org/10.1371/journal.pone.0130998 |
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