Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTA(VP64) expression cassette

Human artificial chromosome (HAC)-based vectors represent an alternative technology for gene delivery and expression with a potential to overcome the problems caused by virus-based vectors. The recently developed alphoid(tetO)-HAC has an advantage over other HAC vectors because it can be easily elim...

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Detalles Bibliográficos
Autores principales: Kononenko, Artem V., Lee, Nicholas C.O., Liskovykh, Mikhail, Masumoto, Hiroshi, Earnshaw, William C., Larionov, Vladimir, Kouprina, Natalay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482055/
https://www.ncbi.nlm.nih.gov/pubmed/25712097
http://dx.doi.org/10.1093/nar/gkv124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482055/
https://www.ncbi.nlm.nih.gov/pubmed/25712097
http://dx.doi.org/10.1093/nar/gkv124

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