A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions

Mutations in human mitochondrial DNA (mtDNA) can cause mitochondrial disease and have been associated with neurodegenerative disorders, cancer, diabetes and aging. Yet our progress toward delineating the precise contributions of mtDNA mutations to these conditions is impeded by the limited availabil...

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Detalles Bibliográficos
Autores principales: Fayzulin, Rafik Z., Perez, Michael, Kozhukhar, Natalia, Spadafora, Domenico, Wilson, Glenn L., Alexeyev, Mikhail F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482060/
https://www.ncbi.nlm.nih.gov/pubmed/25820427
http://dx.doi.org/10.1093/nar/gkv140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482060/
https://www.ncbi.nlm.nih.gov/pubmed/25820427
http://dx.doi.org/10.1093/nar/gkv140

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