DNA damage-induced activation of CUL4B targets HUWE1 for proteasomal degradation

The E3 ubiquitin ligase HUWE1/Mule/ARF-BP1 plays an important role in integrating/coordinating diverse cellular processes such as DNA damage repair and apoptosis. A previous study has shown that HUWE1 is required for the early step of DNA damage-induced apoptosis, by targeting MCL-1 for proteasomal...

Descripción completa

Detalles Bibliográficos
Autores principales: Yi, Juan, Lu, Guang, Li, Li, Wang, Xiaozhen, Cao, Li, Lin, Ming, Zhang, Sha, Shao, Genze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482080/
https://www.ncbi.nlm.nih.gov/pubmed/25883150
http://dx.doi.org/10.1093/nar/gkv325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482080/
https://www.ncbi.nlm.nih.gov/pubmed/25883150
http://dx.doi.org/10.1093/nar/gkv325

Ejemplares similares