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NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway

Trypanosomes mostly regulate gene expression through post-transcriptional mechanisms, particularly mRNA stability. However, much mRNA degradation is cytoplasmic such that mRNA nuclear export must represent an important level of regulation. Ribosomal RNAs must also be exported from the nucleus and th...

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Detalles Bibliográficos
Autores principales: Bühlmann, Melanie, Walrad, Pegine, Rico, Eva, Ivens, Alasdair, Capewell, Paul, Naguleswaran, Arunasalam, Roditi, Isabel, Matthews, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482084/
https://www.ncbi.nlm.nih.gov/pubmed/25873624
http://dx.doi.org/10.1093/nar/gkv330