Variations in periplasmic loop interactions determine the pH-dependent activity of the hexameric urea transporter UreI from Helicobacter pylori: a molecular dynamics study

BACKGROUND: Helicobacter pylori is an important factor in the development of diseases such as ulcer and gastric cancer. This bacterium uses a periplasmic transporter, UreI, to deliver urea to the intracelullar space, where later it is transformed into ammonia by the cytoplasmic enzyme urease to surv...

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Detalles Bibliográficos
Autores principales: Cáceres-Delpiano, Javier, Teneb, Jaime, Mansilla, Rodrigo, García, Apolinaria, Salas-Burgos, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482100/
https://www.ncbi.nlm.nih.gov/pubmed/26112768
http://dx.doi.org/10.1186/s12900-015-0038-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482100/
https://www.ncbi.nlm.nih.gov/pubmed/26112768
http://dx.doi.org/10.1186/s12900-015-0038-0

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