Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice

Adult stem cells (SCs) reside in niches which balance self-renewal with lineage selection and progression during tissue homeostasis. Following injury, culture or transplantation, SCs outside their niche often display fate flexibility(1-4). Here we show that super-enhancers(5) underlie the identity,...

Descripción completa

Detalles Bibliográficos
Autores principales: Adam, Rene C., Yang, Hanseul, Rockowitz, Shira, Larsen, Samantha B., Nikolova, Maria, Oristian, Daniel S., Polak, Lisa, Kadaja, Meelis, Asare, Amma, Zheng, Deyou, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482136/
https://www.ncbi.nlm.nih.gov/pubmed/25799994
http://dx.doi.org/10.1038/nature14289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482136/
https://www.ncbi.nlm.nih.gov/pubmed/25799994
http://dx.doi.org/10.1038/nature14289

Ejemplares similares