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Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice
Adult stem cells (SCs) reside in niches which balance self-renewal with lineage selection and progression during tissue homeostasis. Following injury, culture or transplantation, SCs outside their niche often display fate flexibility(1-4). Here we show that super-enhancers(5) underlie the identity,...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482136/ https://www.ncbi.nlm.nih.gov/pubmed/25799994 http://dx.doi.org/10.1038/nature14289 |