Identification of CREB3L1 as a Biomarker Predicting Doxorubicin Treatment Outcome

BACKGROUND: Doxorubicin has been shown to inhibit proliferation of cancer cells through proteolytic activation of CREB3L1 (cAMP response element binding protein 3-like 1), a transcription factor synthesized as a membrane-bound precursor. Upon doxorubicin treatment, CREB3L1 is cleaved so that the N-t...

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Detalles Bibliográficos
Autores principales: Denard, Bray, Pavia-Jimenez, Andrea, Chen, Weina, Williams, Noelle S., Naina, Harris, Collins, Robert, Brugarolas, James, Ye, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482141/
https://www.ncbi.nlm.nih.gov/pubmed/26110425
http://dx.doi.org/10.1371/journal.pone.0129233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482141/
https://www.ncbi.nlm.nih.gov/pubmed/26110425
http://dx.doi.org/10.1371/journal.pone.0129233

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