Combinatorial Sec pathway analysis for improved heterologous protein secretion in Bacillus subtilis: identification of bottlenecks by systematic gene overexpression

BACKGROUND: Secretory expression of valuable proteins by B. subtilis and its related species has attracted intensive work over the past three decades. Although very high yields can be achieved with homologous proteins, production of heterologous proteins by B. subtilis is unfortunately not the strai...

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Detalles Bibliográficos
Autores principales: Chen, Jingqi, Fu, Gang, Gai, Yuanming, Zheng, Ping, Zhang, Dawei, Wen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482152/
https://www.ncbi.nlm.nih.gov/pubmed/26112883
http://dx.doi.org/10.1186/s12934-015-0282-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482152/
https://www.ncbi.nlm.nih.gov/pubmed/26112883
http://dx.doi.org/10.1186/s12934-015-0282-9

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