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Expression changes of microRNA-1 and its targets Connexin 43 and brain-derived neurotrophic factor in the peripheral nervous system of chronic neuropathic rats

BACKGROUND: MicroRNAs (miRNAs) are involved in the neuroplastic changes which induce and maintain neuropathic pain. However, it is unknown whether nerve injury leads to altered miRNA expression and modulation of pain relevant target gene expression within peripheral nerves. In the present study, exp...

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Detalles Bibliográficos
Autores principales: Neumann, Elena, Hermanns, Henning, Barthel, Franziska, Werdehausen, Robert, Brandenburger, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482165/
https://www.ncbi.nlm.nih.gov/pubmed/26111928
http://dx.doi.org/10.1186/s12990-015-0045-y