CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells

We report anticarcinogenic effects of suicide gene therapy that relies on the use of resveratrol-responsive CArG elements from the Egr-1 promoter to induce GADD45α. In A549 lung cancer cells, endogenous GADD45α was not induced upon resveratrol treatment. Therefore, induction of exogenous GADD45α res...

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Detalles Bibliográficos
Autores principales: Shi, Qiwen, Geldenhuys, Werner, Sutariya, Vijaykumar, Bishayee, Anupam, Patel, Isha, Bhatia, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482243/
https://www.ncbi.nlm.nih.gov/pubmed/26124921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482243/
https://www.ncbi.nlm.nih.gov/pubmed/26124921

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