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The Patterns of Coevolution in Clade B HIV Envelope's N-Glycosylation Sites

The co-evolution of the potential N-glycosylation sites of HIV Clade B gp120 was mapped onto the coevolution network of the protein structure using mean field direct coupling analysis (mfDCA). This was possible for 327 positions with suitable entropy and gap content. Indications of pressure to prese...

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Detalles Bibliográficos
Autores principales: Garimalla, Swetha, Kieber-Emmons, Thomas, Pashov, Anastas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482261/
https://www.ncbi.nlm.nih.gov/pubmed/26110648
http://dx.doi.org/10.1371/journal.pone.0128664