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Mitochondrial DNA polymorphisms, its copy number change and outcome in colorectal cancer
BACKGROUND: Mitochondrion is a small organelle inside the eukaryotic cells. It has its own genome (mtDNA) and encodes for proteins that are critical for energy production and cellular metabolism. Mitochondrial dysfunctions have been implicated in cancer progression and may be related to poor prognos...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482280/ https://www.ncbi.nlm.nih.gov/pubmed/26116242 http://dx.doi.org/10.1186/s13104-015-1250-5 |