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A complete map of potential pathogenicity markers of avian influenza virus subtype H5 predicted from 11 expressed proteins

BACKGROUND: Polybasic cleavage sites of the hemagglutinin (HA) proteins are considered to be the most important determinants indicating virulence of the avian influenza viruses (AIV). However, evidence is accumulating that these sites alone are not sufficient to establish high pathogenicity. There n...

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Detalles Bibliográficos
Autores principales: Khaliq, Zeeshan, Leijon, Mikael, Belák, Sándor, Komorowski, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482282/
https://www.ncbi.nlm.nih.gov/pubmed/26112351
http://dx.doi.org/10.1186/s12866-015-0465-x