PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes

Myocyte function and survival relies on the maintenance of a healthy population of mitochondria. The PINK1/Parkin pathway plays an important role in clearing defective mitochondria via autophagy in cells. However, how the PINK1/Parkin pathway regulates mitochondrial quality control and whether it co...

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Detalles Bibliográficos
Autores principales: Kubli, Dieter A., Cortez, Melissa Q., Moyzis, Alexandra G., Najor, Rita H., Lee, Youngil, Gustafsson, Åsa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482400/
https://www.ncbi.nlm.nih.gov/pubmed/26110811
http://dx.doi.org/10.1371/journal.pone.0130707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482400/
https://www.ncbi.nlm.nih.gov/pubmed/26110811
http://dx.doi.org/10.1371/journal.pone.0130707

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