Characterization of SMAD3 Gene Variants for Possible Roles in Ventricular Septal Defects and Other Congenital Heart Diseases

BACKGROUND: Nodal/TGF signaling pathway has an important effect at early stages of differentiation of human embryonic stem cells in directing them to develop into different embryonic lineages. SMAD3 is a key intracellular messenger regulating factor in the Nodal/TGF signaling pathway, playing import...

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Detalles Bibliográficos
Autores principales: Li, Fei-Feng, Zhou, Jing, Zhao, Dan-Dan, Yan, Peng, Li, Xia, Han, Ying, Li, Xian-Shu, Wang, Gui-Yu, Yu, Kai-Jiang, Liu, Shu-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482402/
https://www.ncbi.nlm.nih.gov/pubmed/26110764
http://dx.doi.org/10.1371/journal.pone.0131542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4482402/
https://www.ncbi.nlm.nih.gov/pubmed/26110764
http://dx.doi.org/10.1371/journal.pone.0131542

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